Home Kit Includes:

– 1 month supply of Semaglutide/B12 Combination Injection
(Dosage varies from 0.25mg – 2.4mg and is dependent on the Month ordered)
– Syringes
– Alcohol Pads
– Physician Consultation [online]

Procedure:

– Subqutaneous (Sub-q) Injection, self-administered in fatty abdominal area or thigh.
– Video tutorial provided after purchase.

Purpose:

Semaglutide Injection is a once-a-week dose that works by mimicking hormones that target areas of the brain involved in regulating appetite and food intake. This can help you eat less and lead to weight loss.
Our Semaglutide is combined with B12 for energy, sleep cycle regulation and a better patient experience.

Dosage and Frequency:

– Once a week – taken on the same day each week, any time of day, with or without food.
– SEE INGREDIENTS BELOW
– Detailed dosing schedule will be provided with the Homekit.

Ingredients:

– Month 1 Homekit: Semaglutide 0.25mg X 4 Injections
– Month 2 Homekit: Semaglutide 0.5mg X 4 Injections
– Month 3 Homekit: Semaglutide 1.0mg X 4 Injections
– Month 4 Homekit: Semaglutide 1.7mg X 4 Injections + Semaglutide 2.4mg X 1 Injections
– Month 5 Homekit: Semaglutide 2.5mg X 4 Injections (Maintenance)

***Please read carefully!

These are NOT ”2 Month Supply” or “3 Month Supply” etc.

ALL OF THE HOMEKITS ARE 4 week SUPPLY!

Diet and Exercise:

Healthy eating and activity are recommended.

Benefits:

– Weight Loss
– May improve Blood Pressure
– May improve cholesterol
– Improves Blood Sugar

Most Common Side Effect (Full list below):

– Nausea
(Recommendations to limit Nausea: Eat bland, low-fat foods, like crackers, toast and rice. Eat foods that contain water, like soup and gelatin. Avoid laying down after eating. Eat slowly. Go outdoors for fresh air.)

TeleHealth Consultation:

A physician may contact you within 24 hours of purchase if additional information is needed.

IMPORTANT!

THIS PRODUCT FOLLOWS A TITRATION SCHEDULE. ALL PATIENTS MUST START WITH ‘MONTH 1’ DOSE. AFTER MONTH 1, THE DOSAGE PER INJECTION INCREASES GRADUALLY IN MONTH 2, 3, AND 4. LASTLY THE MAINTENAINCE DOSE CAN BE ONGOING FOR UP TO 8 MONTHS DEPENDING ON YOUR GOALS

A MINIMUM BMI OF 27 OR GREATER IS REQUIRED TO ORDER THIS PRODUCT

Shipping:

This product can be shipped 2-Day or Overnight and does not need to be refrigerated during shipping. As a precaution, please refrigerate once received and opened.

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The Science Behind Semaglutide

What is Semaglutide?

Semaglutide an incretin mimetic; specifically, semaglutide is a GLP-1 receptor agonist with 94% sequence homology to human GLP-1. Semaglutide binds and activates the GLP-1 receptor. GLP-1 is an important, gut-derived, glucose homeostasis regulator that is released after the oral ingestion of carbohydrates or fats. In patients with Type 2 diabetes, GLP-1 concentrations are decreased in response to an oral glucose load. GLP-1 enhances insulin secretion; it increases glucose-dependent insulin synthesis and in vivo secretion of insulin from pancreatic beta cells in the presence of elevated glucose. In addition to increases in insulin secretion and synthesis, GLP-1 suppresses Glc secretion, slows gastric emptying, reduces food intake, and promotes beta-cell proliferation. The principal mechanism of protraction resulting in the long half-life of semaglutide is albumin binding, which results in decreased renal clearance and protection from metabolic degradation; semaglutide is stabilized against degradation by the DPP-4 enzyme. Semaglutide reduces blood glucose through a mechanism where it stimulates insulin secretion and lowers Glc secretion, both in a glucose-dependent manner. Therefore, when blood glucose is high, insulin secretion is stimulated and Glc secretion is inhibited. The mechanism of blood glucose lowering also involves a minor delay in gastric emptying in the early postprandial phase.

The lack of vitamin B12 may result from any of the following conditions:

• Addisonian (pernicious) anemia — this condition causes autoantibody formation against parietal cells, which results in a lack of IF essential for absorption of vitamin B12 from the intestine

• Malabsorption — impaired absorption of vitamin B12

• Gastrointestinal pathology, dysfunction, or surgery — these include atrophic gastritis, celiac disease, small bowel bacterial overgrowth, pancreatic insufficiency, Helicobacter pylori infection, gastric carcinoma, and total or partial gastrectomy

• Diphyllobothrium latum and related species (the fish tapeworm) infestation — these parasites compete with vitamin B12 for intestinal absorption; this leads to a malabsorption of the vitamin

• Certain medications use — long term metformin use and chronic acid-reducing drugs decrease the absorption of vitamin B12 from food particles

• Malignancy of the pancreas or bowel

• Folic acid deficiency

REFERENCES

1. Once-Weekly Semaglutide in Adults with Overweight or Obesity…READ MORE

2. Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial …READ MORE

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